|Flow Cytometry (Flow)||Assay Dependent|
|Immunohistochemistry (IHC)||Assay Dependent|
|Neutralization (Neu)||Assay Dependent|
|Blocking Assay (BLOCK)||See 3 publications below|
|ELISA (ELISA)||See 1 publications below|
|Flow Cytometry (Flow)||See 1 publications below|
|Immunoprecipitation (IP)||See 1 publications below|
|Tested Species reactivity||Human, Rat|
|Published species reactivity||Rat Human|
|Host / Isotype||Mouse / IgG1, kappa|
|Immunogen||Rat 150 kD alpha4 chain of VLA-4 (CD49d).|
MA49D7 targets CD49d in FACS, IHC, and Neu applications and shows reactivity with Rat and Human samples.
The MA49D7 immunogen is rat 150 kD alpha4 chain of VLA-4 (CD49d).
MA49D7 detects CD49d which has a predicted molecular weight of approximately 111 kDa.
The product of this gene belongs to the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an alpha 4 chain. Unlike other integrin alpha chains, alpha 4 neither contains an I-domain, nor undergoes disulfide-linked cleavage. Alpha 4 chain associates with either beta 1 chain or beta 7 chain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 269C wild type; alpha 4 subunit of VLA-4 receptor; alpha-4 subunit of VLA-4 receptor; antigen CD49D; antigen CD49D, alpha-4 subunit of VLA-4 receptor; CD49 antigen-like family member D; CD49d; Integrin alpha-4; Integrin alpha-IV; ITGA-IV; ITGA4; very late activation protein 4 receptor, alpha 4 subunit; VLA-4 subunit alpha
Gene Aliases: CD49D; IA4; ITGA4
UniProt ID: (Human) P13612
Entrez Gene ID: (Human) 3676
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