|Flow Cytometry (Flow)||Neat|
|Tested Species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||alpha 6 beta 4 integrin purified from A431 cells|
|Storage buffer||PBS with 1% BSA|
|Contains||0.09% sodium azide|
|Storage conditions||4°C or -20°C if preferred, store in dark|
For FACS analysis, use 10ul of the suggested working dilution to label 1x10^6 cells in 100ul.
Integrins are a family of heterodimeric membrane glycoproteins consisting of non-covalently associated alpha and beta subunits. More than 18 alpha and 8 beta subunits with numerous splice variant isoforms have been identified in mammals. In general, integrins function as receptors for extracellular matrix proteins. Certain integrins can also bind to soluble ligands or to counter-receptors on adjacent cells, such as the intracellular adhesion molecules (ICAMs), resulting in aggregation of cells. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis. For integrin subunits alpha3 and alpha6, two cytoplasmic variants, A and B, have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CD49 antigen-like family member F; CD49f; integrin alpha 6; Integrin alpha-6; integrin alpha6B; integrin, alpha 6; ITGA6; ITGA6B; VLA-6
Gene Aliases: CD49f; ITGA6; ITGA6B; VLA-6
UniProt ID: (Human) P23229
Entrez Gene ID: (Human) 3655
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