|Flow Cytometry (Flow)||1 ug/test|
|Immunoprecipitation (IP)||Assay Dependent|
|Western Blot (WB)||Assay Dependent|
|Flow Cytometry (Flow)||See 2 publications below|
|ELISA (ELISA)||See 1 publications below|
|Tested Species reactivity||Rat|
|Published species reactivity||Rat|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Rat beta2 Integrin|
MA1817 targets CD18 in FACS, IP, and WB applications and shows reactivity with Rat samples.
The MA1817 immunogen is rat beta2 Integrin.
MA1817 detects CD18 which has a predicted molecular weight of approximately 83 kDa.
This product is a Low Endotoxin formulation.
The product of this gene belongs to the integrin beta chain family of proteins. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. This gene encodes the integrin beta chain beta 2. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Defects in this gene are the cause of leukocyte adhesion deficiency type I (LAD1). Two transcript variants encoding the same protein have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cd18; CD18 leukocyte adhesion molecule; cluster designation 18; integrin beta-2; Integrin beta-2 subunit; integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit); ITGB2; LAD; LCAMB; Lfa1; macrophage antigen 1 (mac-1) beta subunit); MF17
Gene Aliases: Cd18
Entrez Gene ID: (Rat) 309684
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