|Flow Cytometry (Flow)||1/200 - 1/400|
|Immunofluorescence (IF)||1/200 - 1/1000|
|Western Blot (WB)||1/500 - 1/2000|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Purified recombinant fragment of human JAK3 expressed in E. Coli.|
|Contains||0.03% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
MA5-15561 targets JAK3 in FACS, IF, and WB applications and shows reactivity with Human and mouse samples.
The MA5-15561 immunogen is purified recombinant fragment of human JAK3 expressed in E. Coli.
MA5-15561 detects JAK3 which has a predicted molecular weight of approximately 125kDa.
The protein encoded by this gene is a member of the Janus kinase family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID .
Protein Aliases: JAK-3; JAK3; JAK3_HUMAN; JAKL; Janus kinase 3; Janus kinase 3 (a protein tyrosine kinase, leukocyte); L-JAK; Leukocyte janus kinase; LJAK; Tyrosine-protein kinase JAK3
Gene Aliases: fae; JAK-3; JAK3; JAK3_HUMAN; JAKL; L-JAK; LJAK; wil