|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 503 and 725 of Human JUP|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-29930 targets JUP in IHC (P), IP, and WB applications and shows reactivity with Human samples.
The PA5-29930 immunogen is recombinant fragment corresponding to a region within amino acids 503 and 725 of Human JUP.
This gene encodes a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat. Mutation in this gene has been associated with Naxos disease. Alternative splicing occurs in this gene; however, not all transcripts have been fully described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ARVD12; catenin (cadherin-associated protein); catenin (cadherin-associated protein), gamma 80kDa; Catenin gamma; CTNNG; Desmoplakin III; Desmoplakin-3; DP3; DPIII; gamma (80kD); gamma 80kDa; gamma-catenin; Junction plakoglobin; PDGB; PKGB
Gene Aliases: ARVD12; CTNNG; DP3; DPIII; JUP; PDGB; PKGB
UniProt ID: (Human) P14923
Entrez Gene ID: (Human) 3728
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