|Immunohistochemistry (Paraffin) (IHC (P))||10 - 20 µg/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic 18 amino acid peptide from N-terminus of human KCNJ6 / GIRK2.|
|Purification||Antigen affinity chromatography|
|Contains||< 0.1% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and may be involved in the regulation of insulin secretion by glucose. It associates with two other G-protein-activated potassium channels to form a heteromultimeric pore-forming complex.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: BIR1; G protein-activated inward rectifier potassium channel 2; GIRK-2; GIRK2; HiGIRK2; Inward rectifier K(+) channel Kir3.2; inward rectifier potassium channel KIR3.2; KATP-2; KATP2; KCNJ6; KCNJ7; KIR3.2; Potassium channel, inwardly rectifying subfamily J member 6; potassium channel, inwardly rectifying subfamily J, member 6; Weaver
Gene Aliases: BIR1; GIRK-2; GIRK2; hiGIRK2; KATP-2; KATP2; KCNJ6; KCNJ7; KIR3.2; KPLBS
UniProt ID: (Human) P48051
Entrez Gene ID: (Human) 3763
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