|Immunohistochemistry (Paraffin) (IHC (P))||2.5 µg/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic 17 amino acid peptide from internal region of human KCNMB3.|
|Purification||Antigen affinity chromatography|
|Contains||< 0.1% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
In IHC applications, antigen retrieval using a citrate buffer (pH 6.0) is recommended.
Percent identity with other species by BLAST analysis: Human, Gorilla (100%) Monkey (94%) Bovine, Bat, Horse (88%) Gibbon, Dog, Pig (82%).
MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which may partially inactivate or slightly decrease the activation time of MaxiK alpha subunit currents. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 22.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: big potassium channel beta subunit 3; BK channel beta subunit 3; BK channel subunit beta-3; BKBETA3; calcium-activated potassium channel; calcium-activated potassium channel regulatory subunit; Calcium-activated potassium channel subunit beta-3; Calcium-activated potassium channel, subfamily M subunit beta-3; Charybdotoxin receptor subunit beta-3; HBETA3; K(VCA)beta-3; KCNMB2; KCNMBL; large conductance; large conductance, voltage and Ca2+ activated potassium channel Maxi K beta 3 subunit; Maxi K channel subunit beta-3; MaxiK channel beta-subunit 3; potassium channel subfamily M regulatory beta subunit 3; potassium large conductance calcium-activated channel, subfamily M beta member 3; Slo-beta-3; SLOBETA3; subfamily M subunit beta-3; voltage and Ca2+ activated potassium channel
Gene Aliases: BKBETA3; HBETA3; K(VCA)BETA-3; KCNMB2; KCNMB3; KCNMBL; SLO-BETA-3; SLOBETA3
UniProt ID: (Human) Q9NPA1
Entrez Gene ID: (Human) 27094
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