|Western Blot (WB)||1:500-1:1000|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A synthetic peptide derived from the internal region of human KLF7|
|Purification||Antigen affinity chromatography|
|Storage buffer||Dulbecco's PBS, pH 7.4, with 150mM NaCl, 50% glycerol|
|Contains||0.02% sodium azide|
The protein encoded by this gene is a member of the Kruppel-like transcriptional regulator family. Members in this family regulate cell proliferation, differentiation and survival and contain three C2H2 zinc fingers at the C-terminus that mediate binding to GC-rich sites. This protein may contribute to the progression of type 2 diabetes by inhibiting insulin expression and secretion in pancreatic beta-cells and by deregulating adipocytokine secretion in adipocytes. A pseudogene of this gene is located on the long arm of chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Krueppel-like factor 7; Kruppel-like factor 7 (ubiquitous); Ubiquitous krueppel-like factor; ubiquitous Kruppel-like factor; ubiquitous Kruppel-like transcription factor; UKLF
Gene Aliases: 9830124P08Rik; KLF7; UKLF
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