|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant protein fragment corresponding to a region within amino acids 87 and 260 of Human KLK10|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-30131 targets Kallikrein 10 in WB applications and shows reactivity with Human samples.
The PA5-30131 immunogen is recombinant protein fragment corresponding to a region within amino acids 87 and 260 of Human KLK10.
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 1; breast normal epithelial cell associated serine protease; kallikrein 10; kallikrein 10 protein 1; kallikrein 10 protein 12; kallikrein 10 protein 13; kallikrein 10 protein 2; kallikrein 10 protein 3; kallikrein 10 protein 4; kallikrein 10 protein 5; kallikrein 10 protein 7; kallikrein 10 protein 8; kallikrein 10 protein 9; Kallikrein-10; kallikrein-related peptidase 10; NES1; Normal epithelial cell-specific 1; protease; Protease serine-like 1; protease, serine-like, 1; PRSSL1; serine-like
Gene Aliases: KLK10; NES1; PRSSL1
UniProt ID: (Human) O43240
Entrez Gene ID: (Human) 5655
Molecular Function: annexin calcium-binding protein calmodulin enzyme modulator hydrolase intracellular calcium-sensing protein peptide hormone protease protease inhibitor receptor serine protease signaling molecule
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