|ELISA (ELISA)||5-10 µg/mL|
|Tested Species reactivity||Chemical|
|Host / Isotype||Sheep / IgG|
|Contains||0.09% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA1-75228 specifically detects Ketoprofen.
PA1-75228 has been successfully used in ELISA applications.
The PA1-75228 immunogen is Ketoprofen-BTG.
Ketoprofen is only found in individuals that have used or taken this drug. It is a propionic acid derivative and is a nonsteroidal anti-inflammatory agent (NSAIA) with analgesic and antipyretic properties. The anti-inflammatory effects of ketoprofen are believed to be due to inhibition cylooxygenase-2 (COX-2), an enzyme involved in prostaglandin synthesis via the arachidonic acid pathway. This results in decreased levels of prostaglandins that mediate pain, fever and inflammation. Ketoprofen is a non-specific cyclooxygenase inhibitor and inhibition of COX-1 is thought to confer some of its side effects, such as GI upset and ulceration. Ketoprofen is thought to have anti-bradykinin activity, as well as lysosomal membrane-stabilizing action. Antipyretic effects may be due to action on the hypothalamus, resulting in an increased peripheral blood flow, vasodilation, and subsequent heat dissipation. [National Center for Biotechnology Information. PubChem Compound Database; CID=3825]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: C16H14O3
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