|Flow Cytometry (Flow)||0.1-0.25 µg per 1x10^6 cells|
|Tested Species reactivity||Mouse|
|Host / Isotype||Rat / IgG2a, kappa|
|Immunogen||Mouse CD107a (LAMP-1).|
|Contains||0.1% sodium azide|
|Storage conditions||4° C|
CD107a (lysosome-associated membrane protein-1, LAMP-1), together with LAMP-2, is a major constituent of lysosomal membrane, 1-2% of total CD107a is found also on the plasma membrane. The LAMP proteins are involved in lysosome biogenesis and are required for fusion of lysosomes with phagosomes. Increased CD107a immunoreactivity is observed in neurones, and in glial cells surrounding senile plaques in Alzheimers disease cases and is localized mainly in medullary epithelial cells, single macrophages and lymphocytes in acute thymic involution. CD107a is a good marker of mast cell activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 120 kDa lysosomal membrane glycoprotein; CD107 antigen-like family member A; CD107a; Lamp I; LAMP-1; LAMPA; LGP-120; LGP-A; LGP120; lysosomal membrane glycoprotein 1; Lysosomal membrane glycoprotein A; Lysosome-associated membrane glycoprotein 1; LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN 1 PRECURSOR (LAMP-1) (LGP-A) (LGP-120) (CD107A) (P2B); lysosome-associated membrane protein 1; P2B
Gene Aliases: AI196048; CD107a; Lamp-1; Lamp1
UniProt ID: (Mouse) P11438
Entrez Gene ID: (Mouse) 16783
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