|Western Blot (WB)||1:1000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 130-159 amino acids from the N-terminal region of human LEO1|
|Purification||Antigen affinity chromatography|
|Contains||0.09% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
The PAF1 complex is a multifunctional complex. The PAF1 complex interacts with POLR2A. It may be involved in both initiation and elongation, histone methylation and RNA processing. Overexpression of LEO1 induces cell growth arrest and premature senescence of fibroblasts.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Leo1 Paf1/RNA polymerase II complex component; Leo1, Paf1/RNA polymerase II complex component, homolog; RDL; Replicative senescence down-regulated leo1-like protein; RNA polymerase-associated protein LEO1
Gene Aliases: LEO1; RDL
UniProt ID: (Human) Q8WVC0
Entrez Gene ID: (Human) 123169
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