|Flow Cytometry (Flow)||Assay Dependent|
|Tested Species reactivity||Human, Pig|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Pre-B cell line NALM-6.|
|Storage buffer||TBS, pH 8|
|Contains||15mM sodium azide|
|Storage conditions||4° C, do not freeze|
CD58 (LFA-3) is an immunoglobulin family adhession molecule expressed by both hematopoietic and non-hematopoietic cells (often on antigen presenting cells) and serving as ligand of CD2. This interaction is important for T cell-mediated immunity. CD58 is expressed in transmembrane form and in GPI-anchored form; the later is constitutively associated with protein kinases whereas the transmembrane form activates kinase activity upon triggering. CD58 is a powerful tool for detection of minimal residual disease in acute lymphocytic leukemia, and for evaluation of liver damage related with hepatitis B.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Ag3; CD58; CD58 antigen; CD58 antigen, (lymphocyte function-associated antigen 3); FLJ23181; FLJ43722; LFA-3; LFA3; Lymphocyte function-associated antigen 3; RP5-1086K13.2; Surface glycoprotein LFA-3
Gene Aliases: ag3; CD58; LFA-3; LFA3
UniProt ID: (Human) P19256
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