|Western Blot (WB)||1:1000|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 57-85 amino acids from the N-terminal region of human LINGO1|
|Purification||Antigen affinity chromatography|
|Contains||0.09% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This antibody is predicted to react with mouse and non-human primate based on sequence homology.
LINGO1 is a functional component of the Nogo receptor signaling complex(RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors. It is also an important negative regulator of oligodentrocyte differentiation and axonal myelination.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: LERN1; leucine rich repeat neuronal 6A; leucine-rich repeat; leucine-rich repeat and immunoglobilin domain-containing protein 1; Leucine-rich repeat and immunoglobulin domain-containing protein 1; Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1; leucine-rich repeat neuronal 6A; Leucine-rich repeat neuronal protein 1; Leucine-rich repeat neuronal protein 6A; LRRN6A; UNQ201
Gene Aliases: 4930471K13Rik; AV148400; LERN1; LINGO-1; LINGO1; LRRN6A; UNQ201; UNQ201/PRO227
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