|Western Blot (WB)||1-3 ug/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (RCINSESSTD) corresponding to the internal amino acids of LMTK2|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This antibody is predicted to react with canine, mouse and rat based on sequence homology.
The protein encoded by this gene belongs to the protein kinase superfamily and the protein tyrosine kinase family. It contains N-terminal transmembrane helices and a long C-terminal cytoplasmic tail with serine/threonine/tyrosine kinase activity. This protein interacts with several other proteins, such as Inhibitor-2 , protein phosphatase-1 , p35, and myosin VI. It phosporylates other proteins, and is itself also phosporylated when interacting with cyclin-dependent kinase 5 /p35 complex. This protein involves in nerve growth factor -TrkA signalling, and also plays a critical role in endosomal membrane trafficking. Mouse studies suggested an essential role of this protein in spermatogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: AATYK2; Apoptosis-associated tyrosine kinase 2; Brain-enriched kinase; BREK; CDK5/p35-regulated kinase; CPRK; cyclin-dependent kinase 5/p35-regulated kinase; FLJ46659; hBREK; KIAA1079; kinase phosphatase inhibitor 2; Kinase/phosphatase/inhibitor 2; KPI-2; KPI2; Lemur tyrosine kinase 2; LMR2; LMTK2; protein phosphatase 1, regulatory subunit 100; Serine/threonine-protein kinase KPI-2; Serine/threonine-protein kinase LMTK2
Gene Aliases: AATYK2; BREK; cprk; hBREK; KIAA1079; KPI-2; KPI2; LMR2; LMTK2; PPP1R100
UniProt ID: (Human) Q8IWU2
Entrez Gene ID: (Human) 22853
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