|Immunohistochemistry (Paraffin) (IHC (P))||7 µg/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic 17 amino acid peptide from C-terminal to ligand-binding domain of human NR5A2.|
|Purification||Antigen affinity chromatography|
|Contains||< 0.1% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
Binds to the sequence element 5'-AACGACCGACCTTGAG-3' of the enhancer II of hepatitis B virus genes, a critical cis-element of their expression and regulation. May be responsible for the liver-specific activity of enhancer II, probably in combination with other hepatocyte transcription factors. Key regulator of cholesterol 7-alpha-hydroxylase gene (CYP7A) expression in liver. May also contribute to the regulation of pancreas-specific genes and play important roles in embryonic development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Alpha-1-fetoprotein transcription factor; B1-binding factor; b1-binding factor, hepatocyte transcription factor which activates enhancer II of hepatitis B virus; B1F; B1F2; CPF; CYP7A promoter-binding factor; fetoprotein-alpha 1 (AFP) transcription factor; FTF; FTZ-F1; FTZ-F1beta; HB1F; HB1F-2; Hepatocytic transcription factor; hepatocytic transcription factor hB1F-3; liver nuclear receptor homolog-1 variant 2; Liver receptor homolog 1; Liver receptor homolog-1; LRH-1; LRH1; NR5A2; Nuclear receptor NR5A2; Nuclear receptor phr-1; Nuclear receptor subfamily 5 group A member 2; nuclear receptor subfamily 5, group A, member 2; Receptor phr
Gene Aliases: B1F; B1F2; CPF; FTF; FTZ-F1; FTZ-F1beta; hB1F-2; LRH-1; LRH1; NR5A2
UniProt ID: (Human) O00482
Entrez Gene ID: (Human) 2494
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