|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 105 and 464 of Human LSS|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-28238 targets LSS in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-28238 immunogen is recombinant fragment corresponding to a region within amino acids 105 and 464 of Human LSS.
The protein encoded by this gene catalyzes the conversion of (S)-2,3 oxidosqualene to lanosterol. The encoded protein is a member of the terpene cyclase/mutase family and catalyzes the first step in the biosynthesis of cholesterol, steroid hormones, and vitamin D. Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 2; 2,3-epoxysqualene--lanosterol cyclase; 2,3-epoxysqualene-lanosterol cyclase; 3-epoxysqualene--lanosterol cyclase; 3-epoxysqualene-lanosterol cyclase; hOSC; Lanosterol synthase; OSC; Oxidosqualene--lanosterol cyclase
Gene Aliases: CTRCT44; LSS; OSC
UniProt ID: (Human) P48449
Entrez Gene ID: (Human) 4047
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