|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to a region within amino acids 1802 and 1865 of Human LTRPC7|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 40% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-28101 targets LTRPC7 in WB applications and shows reactivity with Human samples.
The PA5-28101 immunogen is synthetic peptide corresponding to a region within amino acids 1802 and 1865 of Human LTRPC7.
TRPCs, mammalian homologs of the Drosophila transient receptor potential (trp) protein, are ion channels that are thought to mediate capacitative calcium entry into the cell. TRP-PLIK is a protein that is both an ion channel and a kinase. As a channel, it conducts calcium and monovalent cations to depolarize cells and increase intracellular calcium. As a kinase, it is capable of phosphorylating itself and other substrates. The kinase activity is necessary for channel function, as shown by its dependence on intracellular ATP and by the kinase mutants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CHAK; CHAK1; Channel-kinase 1; Long transient receptor potential channel 7; LTRPC ion channel family member 7; LTrpC-7; LTRPC7; Transient receptor potential cation channel subfamily M member 7; transient receptor potential cation channel, subfamily M, member 7; transient receptor potential-phospholipase C-interacting kinase
Gene Aliases: ALSPDC; CHAK; CHAK1; LTrpC-7; LTRPC7; TRP-PLIK; TRPM7
UniProt ID: (Human) Q96QT4
Entrez Gene ID: (Human) 54822
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