|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to a region within amino acids 1 and 45 of Human LXR beta|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 10% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-28127 targets LXR beta in IF and WB applications and shows reactivity with Human samples.
The PA5-28127 immunogen is synthetic peptide corresponding to a region within amino acids 1 and 45 of Human LXR beta.
The LX receptors (LXRs) were originally identified as orphan members of the nuclear receptor superfamily because their ligands were unknown. Like other receptors in the family, LXRs heterodimerize with retinoid X receptor (see MIM 180245) and bind to specific response elements (LXREs) characterized by direct repeats separated by 4 nucleotides. Two genes, alpha (LXRA, MIM 602423) and beta, are known to encode LXR proteins (Song et al., 1995 [PubMed 7625741]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: liver X nuclear receptor beta; Liver X receptor beta; liver X receptor-beta; LX receptor beta; LXR-b; LXRB; NER; NER-I; nuclear orphan receptor LXR-beta; Nuclear receptor NER; Nuclear receptor subfamily 1 group H member 2; nuclear receptor subfamily 1, group H, member 2; Oxysterols receptor LXR-beta; RIP15; steroid hormone-nuclear receptor NER; Ubiquitously-expressed nuclear receptor
Gene Aliases: LXR-b; LXRB; NER; NER-I; NR1H2; RIP15; UNR
UniProt ID: (Human) P55055
Entrez Gene ID: (Human) 7376
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