|Western Blot (WB)||1:1000|
|Tested Species reactivity||Human, Mouse, Non-human primate, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to the sequence of human La Antigen|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/ml BSA, 50% glycerol|
It is not recommended to aliquot this antibody.
La is involved in diverse aspects of RNA metabolism, including binding and protecting 3-prime UUU(OH) elements of newly RNA polymerase III-transcribed RNA, processing 5-prime and 3-prime ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. La protein was originally defined by its reactivity with autoantibodies from patients with Sjogren syndrome and systemic lupus erythematosus (SLE; MIM 152700) (Teplova et al., 2006).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: autoantigen La; La autoantigen; La autoantigen homolog; La protein; La ribonucleoprotein; La ribonucleoprotein domain family, member 3; lupus La antigen; Lupus La protein; Lupus La protein homolog; Lupus LA protein homolog (LA ribonucleoprotein) (LA autoantigen homolog); mRNA for autoantigen; OTTHUMP00000204777; Sjoegren syndrome type B antigen; Sjogren syndrome antigen B (autoantigen La); SS-B; SS-B/La protein
Gene Aliases: La; La/SSB; LARP3; SS-B; SSB
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