|Western Blot (WB)||1:500-1:1000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide, corresponding to amino acids 51-68 (SPVKRPGRKAARVLGSEG) of Human Lig1.|
|Storage buffer||PBS with 0.1mg/ml BSA|
|Contains||0.02% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
PA1-29815 detects Ligase 1 from human samples.
PA1-29815 has been successfully used in Western blot applications.
The PA1-29815 immunogen is: Synthetic peptide, corresponding to amino acids 51-68 (SPVKRPGRKAARVLGSEG) of Human Lig1.
LIG1 encodes DNA ligase I, with functions in DNA replication and the base excision repair process. Mutations in LIG1 that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DNA ligase 1; DNA ligase I; ligase I, DNA, ATP-dependent; MGC117397; MGC130025; Polydeoxyribonucleotide synthase [ATP] 1
Gene Aliases: LIG1
UniProt ID: (Human) P18858
Entrez Gene ID: (Human) 3978
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