|Flow Cytometry (Flow)||1:50|
|Immunohistochemistry (Frozen) (IHC (F))||1:50|
|Western Blot (WB)||1:50|
|Tested Species reactivity||Bacteria|
|Host / Isotype||Mouse / IgG3|
|Storage buffer||tissue culture supernatant|
|Contains||0.02% sodium azide|
|Storage conditions||4° C|
MA1-40134 detects Lipoteichic Acid from gram positive bacterial samples.
MA1-40134 has been successfully used in Western blot, ELISA, flow cytometry, immunofluorescence, and Immunohistochemistry (frozen) applications.
Positive control: Culture medium of Gram-positive bacteria. Negative control: Culture medium of eukaryotic cells.
The MA1-40134 immunogen is LTA.
Lipoteichoic acid (LTA) is a glycerol phosphate surface polymer component of the envelope of Gram-positive bacteria. LTA is anchored via its glycolipids to the membrane and carries a polysaccharide chain extending into the peptidoglycan layer of the cell wall. LTA is released spontaneously into the culture medium during growth of gram-positive bacteria. LTA functions as an immune activator with characteristics very similar to lipopolysaccharide (LPS) from Gram-negative bacteria. LTA binds to CD14 and triggers activation predominantly via Toll-like receptor 2. Although LTA is internalized and traffics to the Golgi, the cellular activation in response to LTA occurs at the cell surface.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: LTA
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