|Western Blot (WB)||1 µg/ml|
|Tested Species reactivity||Human, Mouse, Rat, Xenopus|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to residues L(348) N H T I L A G V H S N D H S V V(364) of human LPA1.|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS with 1mg/ml BSA|
|Contains||0.05% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA1-1041 detects lysophosphatidic acid receptor 1 protein in rat, human, mouse, and Xenopus samples.
PA1-1041 has successfully been used in Western blot procedures. By Western blot, this antibody detects an ~42 kDa protein representing lysophosphatidic acid receptor 1 in PC12 and HeLa whole cell lysates as well as mouse and Xenopus liver samples.
The PA1-1041 immunogen is a synthetic peptide corresponding to residues L(348) N H T I L A G V H S N D H S V V(364) of human LPA1. The immunizing sequence is completely conserved in human, mouse, rat and bovine. This peptide (Cat. # PEP-233) is available for use in neutralization and control experiments.
Lysophosphatidic acid receptor 1 (LPA1, EDG2, VZG-1) is a seven transmembrane receptor coupled to G proteins and has high affinity to lypophosphatidic acid (LPA). LPA1 is a member of the EDG-family of receptors which includes LPA1, LPA2 and LPA3.
These receptors mediate the serum borne lipid mediator LPA for a variety biological functions. The activation of LPA1 by LPA has shown to stimulate cell spreading and motility, mitogenesis, and various other nervous system activities.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: EDG2; endothelial differentiation lysophosphatidic acid G-protein-coupled receptor 2; endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 2; G-protein coupled receptor 26; LPA receptor 1; LPA-1; LPA1; Lysophosphatidic acid receptor 1; Lysophosphatidic acid receptor Edg-2; Rec1.3; ventricular zone gene 1; VZG-1
Gene Aliases: AI326300; edg-2; EDG2; Gpcr26; Gpcr91; GPR26; Kdt2; LPA1; LPAR1; Mrec1.3; rec.1.3; vzg-1; VZG1
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.