|Flow Cytometry (Flow)||1:25-1:50|
|Functional Assay (FN)||Assay Dependent|
|Tested Species reactivity||Mouse, Rat|
|Host / Isotype||Rat / IgG1|
|Immunogen||RAW 264 cells|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
For FACS analysis, use 10ul of the suggested working dilution to label 1x10^6 cells in 100ul.
The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: C-FMS; CD115; CD115 antigen; colony stimulating factor 1 receptor; CSF-1 receptor; CSF-1-R; CSF1R; CSFR; FIM2; FMS; FMS proto-oncogene; macrophage colony stimulating factor I receptor; Macrophage colony-stimulating factor 1 receptor; McDonough feline sarcoma viral v-fms oncogene homolog; Proto-oncogene c-Fms; proto-oncogene fms
Gene Aliases: AI323359; c-fms; CD115; CSF-1-R; CSF-1R; Csf1r; Csfmr; Fim-2; Fms; M-CSF-R; M-CSFR; mrfms
UniProt ID: (Mouse) P09581
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.