|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 1 and 162 of Human MAFG|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 20% glycerol|
|Contains||0.025% Proclin 300|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-30086 targets MAFG in IF, IHC (P), and WB applications and shows reactivity with Human, Mouse and Rat samples.
The PA5-30086 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 162 of Human MAFG.
Globin gene expression is regulated through nuclear factor erythroid-2 (NFE2) elements located in enhancer-like locus control regions positioned many kb upstream of alpha- and beta-gene clusters (summarized by Blank et al., 1997 [PubMed 9166829]). NFE2 DNA-binding activity consists of a heterodimer containing a ubiquitous small Maf protein (MafF, MIM 604877; MafG; or MafK, MIM 600197) and the tissue-restricted protein p45 NFE2 (MIM 601490). Both subunits are members of the activator protein-1-like superfamily of basic leucine zipper (bZIP) proteins (see MIM 165160).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: avian musculoaponeurotic fibrosarcoma virus (v-maf) AS42 oncogene, protein G; basic leucine zipper transcription factor MafG; hMAF; Transcription factor MafG; v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G; v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G; V-maf musculoaponeurotic fibrosarcoma oncogene homolog G
Gene Aliases: AA545192; C630022N07Rik; hMAF; MAFG
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