|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 901 and 1120 of Human MAP4K6|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-28901 targets MAP4K6 in IF and WB applications and shows reactivity with Human samples.
The PA5-28901 immunogen is recombinant fragment corresponding to a region within amino acids 901 and 1120 of Human MAP4K6.
This gene encodes a serine/threonine kinase belonging to the germinal center kinase (GCK) family. The protein is structurally similar to the kinases that are related to NIK and may belong to a distinct subfamily of NIK-related kinases within the GCK family. Studies of the mouse homolog indicate an up-regulation of expression in the course of postnatal mouse cerebral development and activation of the cJun N-terminal kinase (JNK) and the p38 pathways. Alternative splicing occurs at this locus and four transcript variants encoding distinct isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: B55; GCK family kinase MINK; hMINK; hMINKbeta; MAP4K6; MAPK/ERK kinase kinase kinase 6; MEK kinase kinase 6; MEKKK 6; MINK; Misshapen-like kinase 1; Misshapen/NIK-related kinase; Mitogen-activated protein kinase kinase kinase kinase 6; serine/threonine protein kinase; YSK2; ZC3
Gene Aliases: B55; MAP4K6; MINK; MINK1; YSK2; ZC3
UniProt ID: (Human) Q8N4C8
Entrez Gene ID: (Human) 50488
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