|Immunohistochemistry (Paraffin) (IHC (P))||8 - 10 µg/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic 16 amino acid peptide from 1st cytoplasmic domain of human MAS1.|
|Purification||Antigen affinity chromatography|
|Contains||< 0.1% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
Percent identity with other species by BLAST analysis: Human, Gorilla, Monkey, Mouse, Rat, Bovine, Dolphin, Hamster, Elephant, Panda, Pig, Opossum (100%) Platypus (94%).
The structure of the MAS1 product indicates that it belongs to the class of receptors that are coupled to GTP-binding proteins and share a conserved structural motif, which is described as a '7-transmembrane segment' following the prediction that these hydrophobic segments form membrane-spanning alpha-helices. The MAS1 protein may be a receptor that, when activated, modulates a critical component in a growth-regulating pathway to bring about oncogenic effects.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: MAS; Mas proto-oncogene; Mas-related G protein-coupled receptor A; MAS1; MAS1 oncogene; Proto-oncogene Mas
Gene Aliases: MAS; MAS1; MGRA
UniProt ID: (Human) P04201
Entrez Gene ID: (Human) 4142
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