|Immunohistochemistry (Paraffin) (IHC (P))||10 µg/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic 19 amino acid peptide from internal region of human MC5 Receptor.|
|Purification||Antigen affinity chromatography|
|Contains||< 0.1% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
In IHC applications, antigen retrieval using Proteinase K treatment is recommended.
Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Monkey (100%) Marmoset, Mouse, Hamster, Panda (95%) Rabbit (89%).
MC5R, a Melanocortin Receptor, mediates the effects of melanocyte-stimulating hormone (MSH) and adrenocorticotropic hormone (ACTH), and activates adenylate cyclase. This receptor controls multiple functions in the brain and in peripheral tissues, such as thermoregulation, immunomodulation, appetite control, and sexual behavior. Melanocortin 5 receptor has been reported to be expressed in a variety of tissues, especially in pituitary, exocrine glands, reproductive organs, lung, kidney, and esophagus. No human ESTs have been isolated.
Protein Aliases: HMC5R; MC-2; MC2; MC5; MC5 receptor; MC5-R; MC5R; Melanocortin 5 receptor; Melanocortin receptor 5; Melanocortin-5 receptor
Gene Aliases: MC2; MC5R
UniProt ID: (Human) P33032
Entrez Gene ID: (Human) 4161