|Western Blot (WB)||1/500 - 1/2000|
|Tested Species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Purified recombinant fragment of DDR1 (aa602-681) expressed in E. Coli.|
|Contains||0.03% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
MA5-15429 targets DDR1 in WB applications and shows reactivity with Human samples.
The MA5-15429 immunogen is purified recombinant fragment of DDR1 (aa602-681) expressed in E. Coli.
Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain, and that are activated by various types of collagen. Expression of this protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, it has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CAK; CD167; CD167 antigen-like family member A; CD167a; Cell adhesion kinase; DAAP-278B20.1; DDR; Discoidin receptor tyrosine kinase; EDDR1; Epithelial discoidin domain receptor 1; Epithelial discoidin domain-containing receptor 1; HGK2; Mammary carcinoma kinase 10; MCK-10; MCK10; neuroepithelial tyrosine kinase; neurotrophic tyrosine kinase, receptor, type 4; NTRK4; Protein-tyrosine kinase 3A; Protein-tyrosine kinase RTK-6; PTK3; PTK3A; PTK3A protein tyrosine kinase 3A; RTK6; TRK E; TRKE; Tyrosine kinase DDR; Tyrosine-protein kinase CAK
Gene Aliases: CAK; CD167; DDR; DDR1; EDDR1; HGK2; MCK10; NEP; NTRK4; PTK3; PTK3A; RTK6; TRKE
UniProt ID: (Human) Q08345
Entrez Gene ID: (Human) 780
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