|Western Blot (WB)||1 µg/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide - Immunogen sequence information is commercially sensitive.|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS with 2% sucrose|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA1-27958 detects MDM4 from human samples.
PA1-27958 may be successfully used in Western blot applications. Use at a concentration of 1µg/ml in 5% skim milk/PBS buffer.
The PA1-27646 immunogen is a synthetic peptide with a commercially sensitive sequence.
MDM4 inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. inhibits degradation of MDM2. It can reverse MDM2-targeted degradation of p53 while maintaining suppression of p53 transactivation and apotopic functions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DKFZp781B1423; Double minute 4 protein; double minute 4, human homolog of; p53-binding protein; HDMX; Mdm2-like p53-binding protein; Mdm4 p53 binding protein homolog; MDM4 protein variant G; MDM4 protein variant Y; MDM4-related protein 1; MDMX; MGC132766; p53-binding protein Mdm4; Protein Mdm4; Protein Mdmx; RP11-430C7.1
Gene Aliases: HDMX; MDM4; MDMX; MRP1
UniProt ID: (Human) O15151
Entrez Gene ID: (Human) 4194
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