|Immunohistochemistry (Paraffin) (IHC (P))||5 µg/ml|
|Tested Species reactivity||Dog, Chicken, Horse, Human, Mouse, Rat, Xenopus|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide (296 THPYPSEEQKKQLAQD 311) of MEIS1 protein.|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS with 0.05% BSA|
|Contains||0.05% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
MEIS1, also known as Homeobox protein Meis1, is a nuclear protein belonging to the TALE/MEIS homeobox family with a homeobox DNA-binding domain. It acts as a transcriptional regulator of PAX6 (Paired box protein Pax-6). It is a protein required for hematopoiesis, megakaryocyte lineage development and vascular patterning. Expression is seen at low levels in normal immunohepatopoietic tissues, and in a subset of myeloid leukemia cell lines, with the highest expression seen in those with a megakaryocytic-erythroid phenotype. It is also expressed at high levels in the cerebellum.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Homeobox protein Meis1; leukemogenic homolog protein; Meis1; Meis1, myeloid ecotropic viral integration site 1 homolog; myeloid ecotropic viral insertion site-1a protein; Myeloid ecotropic viral integration site 1; myeloid ecotropic viral integration site 1 homolog; WUGSC:H_NH0444B04.1; XMeis1; XMeis1-2 protein
Gene Aliases: C530044H18Rik; Evi8; MEIS1
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