|Immunohistochemistry (Paraffin) (IHC (P))||1:10-1:50|
|Western Blot (WB)||1:1000|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 206-234 amino acids from the C-terminal region of human MESDC2|
|Purification||Antigen affinity chromatography|
|Contains||0.09% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
Chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs). Acts as a modulator of the Wnt pathway through chaperoning the coreceptors of the canonical Wnt pathway, LRP5 and LRP6, to the plasma membrane. Essential for specification of embryonic polarity and mesoderm induction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: KIAA0081; LDLR chaperone MESD; MESD; MESDC2; Mesoderm development candidate 2; Mesoderm development protein; Renal carcinoma antigen NY-REN-61
Gene Aliases: 2210015O11Rik; AW537813; BOCA; KIAA0081; MESD; MESDC2; mKIAA0081; msd; UNQ1911/PRO4369
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