|Immunohistochemistry (Paraffin) (IHC (P))||5 µg/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic 18 amino acid peptide from internal region of human MINK1 / MAP4K6.|
|Purification||Antigen affinity chromatography|
|Contains||< 0.1% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
In IHC applications, antigen retrieval using a citrate buffer (pH 6.0) is recommended.
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Bat, Hamster, Elephant, Panda, Horse, Pig, Opossum (100%).
This gene encodes a serine/threonine kinase belonging to the germinal center kinase family. The protein is structurally similar to the kinases that are related to NIK and may belong to a distinct subfamily of NIK-related kinases within the GCK family. Studies of the mouse homolog indicate an up-regulation of expression in the course of postnatal mouse cerebral development and activation of the cJun N-terminal kinase and the p38 pathways. Alternative splicing occurs at this locus and four transcript variants encoding distinct isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: B55; GCK family kinase MINK; hMINK; hMINKbeta; MAP4K6; MAPK/ERK kinase kinase kinase 6; MEK kinase kinase 6; MEKKK 6; MINK; Misshapen-like kinase 1; Misshapen/NIK-related kinase; Mitogen-activated protein kinase kinase kinase kinase 6; serine/threonine protein kinase; YSK2; ZC3
Gene Aliases: B55; MAP4K6; MINK; MINK1; YSK2; ZC3
UniProt ID: (Human) Q8N4C8
Entrez Gene ID: (Human) 50488
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