|Immunohistochemistry (Paraffin) (IHC (P))||1:50-1:100|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A synthetic peptide derived from the internal region of human MLK1/2|
|Purification||Antigen affinity chromatography|
|Storage buffer||Dulbecco's PBS, pH 7.4, with 150mM NaCl, 50% glycerol|
|Contains||0.02% sodium azide|
MLK is a member of the serine/threonine kinase family. This kinase has been shown to activate MAPK8/JNK and MKK4/SEK1, and this kinase itself can be phoshorylated, and thus activated by JNK kinases. This kinase functions preferentially on the JNK signaling pathway, and is reported to be involved in nerve growth factor (NGF) induced neuronal apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: MAP3K9, MEKK9, MLK1, Mixed lineage kinase 1, PRKE1, Mixed lineage kinase 2, Mitogen-activated protein kinase kinase kinase 10, Protein kinase MST, Mixed lineage kinase 2; mitogen activated protein kinase kinase kinase 9; Mitogen-activated protein kinase kinase kinase 10; Mitogen-activated protein kinase kinase kinase 9; Mixed lineage kinase 1; mixed lineage kinase 1 (tyr and ser/thr specificity); Mixed lineage kinase 2; MKN28 derived nonreceptor_type; MKN28 derived nonreceptor_type serine/threonine kinase; MKN28 kinase; Protein kinase MST; serine/threonine kinase
Gene Aliases: BC028668; BC046514; E130314H24Rik; MAP3K10; MAP3K9; MEKK10; MEKK9; MLK1; MLK2; MST; PRKE1
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