|Immunofluorescence (IF)||Assay Dependent|
|Western Blot (WB)||2-4 µg/ml|
|Immunohistochemistry (IHC)||See 2 publications below|
|Tested Species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG1, kappa|
|Immunogen||APMA (4-Aminophenylmercuric acetate) activated Human stromelysin-1 (SL-1)|
|Storage buffer||PBS, pH 7.4, with 0.2% BSA|
|Contains||0.09% sodium azide|
|Storage conditions||4° C|
MA5-14199 targets MMP-3 (Stromelysin-1) in IF and WB applications and shows reactivity with Human samples.
The MA5-14199 immunogen is aPMA (4-Aminophenylmercuric acetate) activated Human stromelysin-1 (SL-1).
Matrix metalloproteinases (MMP) are proteolytic enzymes capable of degrading connective tissue components. Imbalanced secretion of certain MMP or disturbances in the differential control of MMP by tissue inhibitor of MMPs (TIMPs) are implicated in the invasive potential of malignant tumors. Stromelysin (MMP3/Transin) degrades several matrix components including the core proteins of proteoglycans, laminin and non-helical regions of collagens.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: matrix metalloproteinase 3 (stromelysin 1; matrix metalloproteinase 3 (stromelysin 1, progelatinase); Matrix metalloproteinase-3; MMP-3; progelatinase); proteoglycanase; SL-1; Stromelysin-1; Transin-1
Gene Aliases: CHDS6; MMP-3; MMP3; SL-1; STMY; STMY1; STR1
UniProt ID: (Human) P08254
Entrez Gene ID: (Human) 4314
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