|ELISA (ELISA)||Assay dependent|
|Functional Assay (FN)||Assay-dependent|
|Immunohistochemistry (Paraffin) (IHC (P))||1:20|
|Western Blot (WB)||1:1000-1:2000|
|Tested Species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Amino acids 182-582 of Mre11 expressed in E. coli.|
|Storage buffer||PBS, pH 7.4|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
MA1-23253 detects MRE11 in Human samples.
MA1-23253 has been successfully used in ELISA, Immunofluorescence, Immunoprecipitation, Western Blot and Immunohistochemistry procedures.
MA1-23253 immunogen corresponds to Amino acids 182-582 of Mre11 expressed in E. coli..
Mre11 is an 80 kDa protein that acts as a Mn+2 dependent double stranded DNA 3' to 5' exonuclease and a single stranded DNA endonuclease. It is part of a larger complex with Rad50, p95 (Nibrin) and possibly other associated proteins involved in the nucleolytic end-processing of double strand breaks and telomere maintenance.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: AT-like disease; ATLD; DNA recombination and repair protein; Double-strand break repair protein MRE11; Double-strand break repair protein MRE11A; endo/exonuclease Mre11; HNGS1; Meiotic recombination 11 homolog 1; Meiotic recombination 11 homolog A; MRE11; MRE11 double strand break repair nuclease A; MRE11 homolog 1; MRE11 homolog A; MRE11 homolog, double strand break repair nuclease A; MRE11 meiotic recombination 11 homolog A; MRE11 meiotic recombination 11-like protein A; MRE11B
Gene Aliases: ATLD; HNGS1; MRE11; MRE11A; MRE11B
UniProt ID: (Human) P49959
Entrez Gene ID: (Human) 4361
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