|Western Blot (WB)||1:300-1:2000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit|
|Immunogen||A synthetic peptide from human Mas-related G-protein coupled receptor member X1, X3 and X4|
|Storage buffer||whole serum|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
Reconstitute with 100 ul of distilled water.
Centrifuge to remove any insoluble material.
Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells. G(alpha)q proteins are involved in the calcium-signaling pathway. Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: G protein-coupled receptor MRGX1; G protein-coupled receptor MRGX3; G protein-coupled receptor MRGX4; G protein-coupled receptor SNSR1; G protein-coupled receptor SNSR2; G protein-coupled receptor SNSR3; G protein-coupled receptor SNSR5; G protein-coupled receptor SNSR6; Mas-related G protein-coupled receptor G2; Mas-related G-protein coupled receptor member X1; Mas-related G-protein coupled receptor member X1, X3, X4; Mas-related G-protein coupled receptor member X3; Mas-related G-protein coupled receptor member X4; mas-related GPCR member X3; MAS-related GPR, member X1; MAS-related GPR, member X3; MAS-related GPR, member X4; Sensory neuron-specific G-protein coupled receptor 1/2; Sensory neuron-specific G-protein coupled receptor 3/4; Sensory neuron-specific G-protein coupled receptor 3/4, MRGX1, SNSR3, SNSR4, GPCR, MAS-relat; Sensory neuron-specific G-protein coupled receptor 5/6
Gene Aliases: GPCR; MGRG2; MRGPRX1; MRGPRX3; MRGPRX4; MRGX1; MRGX3; MRGX4; SNSR1; SNSR2; SNSR3; SNSR4; SNSR5; SNSR6
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