|Immunohistochemistry (Paraffin) (IHC (P))||21 µg/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic 17 amino acid peptide from 1st extracellular domain of human MRGPRX3 / MRGX3.|
|Purification||Antigen affinity chromatography|
|Contains||< 0.1% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
Percent identity with other species by BLAST analysis: Human (100%) Gorilla (94%) Monkey (82%).
Orphan receptor activated by a subset of RFamide-family neuropeptides such as FLRF-amide and FMRF-amide. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. May regulate the function of nociceptive neurons by modulation of pain perception. Expressed in a subset of IB4-positive small diameter nociceptive dorsal root neurons.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: G protein-coupled receptor MRGX3; G protein-coupled receptor SNSR1; G protein-coupled receptor SNSR2; Hdrr1; HDRR2; Mas-related G-protein coupled receptor member X3; Mas-related GPCR member X3; MAS-related GPR; MAS-related GPR, member X3; member X3; MRGPRX3; MRGX3; Sensory neuron-specific G-protein coupled receptor 1/2; SNSR1; SNSR2
Gene Aliases: GPCR; MRGPRX3; MRGX3; SNSR1; SNSR2
UniProt ID: (Human) Q96LB0
Entrez Gene ID: (Human) 117195
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