|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant protein fragment corresponding to a region within amino acids 1 and 177 of Human MRPL10|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-31245 targets MRPL10 in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-31245 immunogen is recombinant protein fragment corresponding to a region within amino acids 1 and 177 of Human MRPL10.
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found on chromosome 5q.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 39S ribosomal protein L10; 39S ribosomal protein L10, mitochondrial; 39S ribosomal protein L8; 39S ribosomal protein L8, mitochondrial; L10MT; L8mt; mitochondrial; Mitochondrial large ribosomal subunit protein uL10m; MRP-L10; MRP-L8; MRPL8; RPML8
Gene Aliases: L10MT; MRP-L10; MRP-L8; MRPL10; MRPL8; RPML8
UniProt ID: (Human) Q7Z7H8
Entrez Gene ID: (Human) 124995
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