|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 1 and 208 of Human MRPL39|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 1% BSA, 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-31983 targets MRPL39 in WB applications and shows reactivity with Human samples.
The PA5-31983 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 208 of Human MRPL39.
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Two transcript variants encoding distinct isoforms have been described. A pseudogene corresponding to this gene is found on chromosome 5q.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 39S ribosomal protein L39; 39S ribosomal protein L39, mitochondrial; 39S ribosomal protein L5; 39S ribosomal protein L5, mitochondrial; C21orf92; L39mt; L5mt; mitochondrial; Mitochondrial large ribosomal subunit protein mL39; MRP-L39; MRPL5; PRED22; PRED66; RPML5
Gene Aliases: C21orf92; L39mt; MRP-L5; MRPL39; MRPL5; MSTP003; PRED22; PRED66; RPML5
UniProt ID: (Human) Q9NYK5
Entrez Gene ID: (Human) 54148
Molecular Function: ligase
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