|Immunocytochemistry (ICC)||5 ug/ml|
|Immunofluorescence (IF)||20 µg/ml|
|Western Blot (WB)||1 ug/mL|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A 17 amino acid peptide near the carboxy terminus of human MTERFD1|
|Purification||Antigen affinity chromatography|
|Contains||0.02% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
A suggested positive control is NIH-3T3 cell lysate.
PA5-34530 can be used with blocking peptide PEP-1573.
Members of the mTERF (mitochondrial transcription termination factor) family, are mitochondrial proteins that are believed to be transcription termination factors. MTERFD1 is composed of three leucine zippers that form a three-stranded coiled-coil that binds to DNA. It binds promoter DNA and acts as a mitochondrial transcription regulator. It has been suggested that only the phosphorylated form of MTERFD1 has transcription termination activity. A closely related mTERF family member, MTERFD3, is believed to be involved in cell cycle regulation and cell growth by modulating mitochondrial transcription.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CGI-12; Mitochondrial transcription termination factor 3; MTERF domain containing 1; mTERF domain-containing protein 1; mTERF domain-containing protein 1, mitochondrial; mTERF3; MTERFD1; Transcription termination factor 3, mitochondrial
Gene Aliases: 2410017I18Rik; CGI-12; MTERF3; MTERFD1
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