|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 579 and 753 of MTF1|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This gene encodes a transcription factor that induces expression of metallothioneins and other genes involved in metal homeostasis in response to heavy metals such as cadmium, zinc, copper, and silver. The protein is a nucleocytoplasmic shuttling protein that accumulates in the nucleus upon heavy metal exposure and binds to promoters containing a metal-responsive element (MRE). [provided by RefSeq].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Metal regulatory transcription factor 1; metal-regulatory transcription factor 1; metal-responsive transcription factor 1; MRE-binding transcription factor; MRE-binding transcription factor-1; MTF-1; Transcription factor MTF-1; zinc regulatory factor; ZRF
Gene Aliases: MTF-1; MTF1; ZRF
UniProt ID: (Human) Q14872
Entrez Gene ID: (Human) 4520
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