|Immunohistochemistry (Paraffin) (IHC (P))||1:50-1:100|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A synthetic peptide derived from the internal region of human MTG16|
|Purification||Antigen affinity chromatography|
|Storage buffer||Dulbecco's PBS, pH 7.4, with 50% glycerol, 150mM NaCl|
|Contains||0.02% sodium azide|
This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(16;21)(q24;q22) translocation is one of the less common karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. This gene is also a putative breast tumor suppressor. Alternative splicing results in transcript variants. [provided by RefSeq, Nov 2010].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cbfa2t3h; core-binding factor, runt domain, alpha subunit 2; translocated to, 3; Eight twenty one protein 2; ETO/MTG8-related protein ETO-2; hMTG16; MTG16HEL; MTG8-related gene 2; MTG8-related protein 2; Mtgr2; myeloid translocation gene 8 and 16b; Myeloid translocation gene on chromosome 16 protein; myeloid translocation gene-related protein 2; Protein CBFA2T3; Protein ETO-2; Zinc finger MYND domain-containing protein 4
Gene Aliases: A630044F12Rik; AI465270; AW229127; CBFA2T3; Cbfa2t3h; ETO-2; ETO2; MTG16; MTGR2; RUNX1T3; ZMYND4
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