|Western Blot (WB)||Assay Dependent|
|Tested Species reactivity||Human|
|Host / Isotype||Sheep / IgG|
|Immunogen||C-terminal portion of recombinant MTGR1.|
|Purification||Ammonium sulfate precipitation|
|Contains||0.08% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
Myeloid tumor related gene (MTGR1) is found deleted in acute myeloid leukemia. Overexpression of MTGR1 can stimulate AML1-MTG8 to induce GCSF- dependent proliferation of L-G cells and to interfere with AML1- dependent transcription. AML1/MTG8 functions as a complex with MTGR1 and that the complex might be important in promoting leukemogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: core-binding factor, runt domain, alpha subunit 2; translocated to, 2; DKFZp313F2116; EHT; ETO homolog on chromosome 20; ETO homologous on chromosome 20; MTG8-like protein; MTG8-related protein 1; myeloid translocation gene-related protein 1; Myeloid translocation-related protein 1; p85; Protein CBFA2T2; ZMYND3 CBFA2T2
Gene Aliases: CBFA2T2; EHT; MTGR1; p85; ZMYND3
UniProt ID: (Human) O43439
Entrez Gene ID: (Human) 9139
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