|Immunofluorescence (IF)||1/200 - 1/1000|
|Immunohistochemistry (Paraffin) (IHC (P))||1/200 - 1/1000|
|Tested Species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Purified recombinant extracellular fragment of human MUSK (aa24-209) fused with hIgGFc tag expressed in HEK293 cell line.|
|Contains||0.03% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
MA5-15518 targets MUSK in IF and IHC applications and shows reactivity with Human samples.
The MA5-15518 immunogen is purified recombinant extracellular fragment of human MUSK (aa24-209) fused with hIgGFc tag expressed in HEK293 cell line.
MA5-15518 detects MUSK which has a predicted molecular weight of approximately 97kDa.
This gene encodes a muscle-specific tyrosine kinase receptor. The encoded protein may play a role in clustering of the acetylcholine receptor in the postsynaptic neuromuscular junction. Mutations in this gene have been associated with congenital myasthenic syndrome. Alternatively spliced transcript variants have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: MGC126323; MGC126324; Muscle, skeletal receptor tyrosine-protein kinase; muscle, skeletal, receptor tyrosine kinase; muscle-specific kinase receptor; Muscle-specific tyrosine-protein kinase receptor; MUSK
Gene Aliases: CMS9; FADS; MUSK
UniProt ID: (Human) O15146
Entrez Gene ID: (Human) 4593
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