|Immunofluorescence (IF)||5 ug/mL|
|Immunohistochemistry (IHC)||5 ug/mL|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A 12 amino acid synthetic peptide near the carboxy terminus of human MYBPC1|
|Purification||Antigen affinity chromatography|
|Contains||0.02% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
A suggested positive control is human skeletal muscle tissue lysate.
PA5-34340 can be used with blocking peptide PEP-1383.
Myosin binding protein C (MYBPC) is a component of the thick filament of striated muscle, with the slow-type isoform designated MYBPC1. Both the fast-type (MYBPC2) and slow-type MYBPC protein contains seven immunoglobulin C2 motifs and three fibronectin type-III repeats. Multiple isoforms of MYBPC1 are known to exist, and are present in varying amounts in different skeletal muscles. It is thought that the MYBPC1 slow subfamily may play important roles in the assembly and stabilization of sarcomeric M- and A-bands and regulate the contractile properties of the actomyosin filaments.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: C-protein, skeletal muscle slow isoform; MYBPC1; MYBPCC; MYBPCS; Myosin-binding protein C slow type; Myosin-binding protein C, slow-type; skeletal muscle C-protein; Slow MyBP-C
Gene Aliases: LCCS4; MYBPC1; MYBPCC; MYBPCS
UniProt ID: (Human) Q00872
Entrez Gene ID: (Human) 4604
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