|Western Blot (WB)||1-3 ug/ml|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (ETKQLELDLN) corresponding to the internal amino acids of MYO5A|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This antibody is predicted to react with bovine and rat based on sequence homology.
This gene is one of three myosin V heavy-chain genes, belonging to the myosin gene superfamily. Myosin V is a class of actin-based motor proteins involved in cytoplasmic vesicle transport and anchorage, spindle-pole alignment and mRNA translocation. The protein encoded by this gene is abundant in melanocytes and nerve cells. Mutations in this gene cause Griscelli syndrome type-1 and neuroectodermal melanolysosomal disease, or Elejalde disease. Multiple alternatively spliced transcript variants encoding different isoforms have been reported, but the full-length nature of some variants has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: dilute; dilute lethal-20J protein; Dilute myosin heavy chain, non-muscle; flailer; MYH12; MYO5; MYO5A; Myosin heavy chain 12; myosin V; myosin VA; myosin VA (heavy chain 12, myoxin); myosin, heavy polypeptide kinase; Myosin-12; myosin-Va; Myoxin; MYR12; Unconventional myosin-Va
Gene Aliases: 9630007J19Rik; AI413174; AI661011; d; d-120J; Dbv; Dilute; flail; flr; GS1; MVa; MYH12; MYO5; MYO5A; MyoVA; MYR12; Sev-1
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