|Immunohistochemistry (Paraffin) (IHC (P))||1:10-1:100|
|Western Blot (WB)||1:20-1:200|
|Immunohistochemistry (IHC)||See 12 publications below|
|Western Blot (WB)||See 1 publications below|
|Tested Species reactivity||Human|
|Published species reactivity||Non-human primate Human|
|Host / Isotype||Mouse / IgG2a, kappa|
|Immunogen||Recombinant protein corresponding to N-terminal region of human Maspin|
|Storage buffer||tissue culture supernatant|
|Contains||0.09% sodium azide|
|Storage conditions||4° C|
MA5-12383 targets Maspin in IHC (P) and WB applications and shows reactivity with human samples. In Western blot testing, this antibody did not cross-react with mouse samples.
The MA5-12383 immunogen is recombinant protein corresponding to N-terminal region of human Maspin.
Maspin or mammary-specific serpin is a tumor suppressor protein of serine proteinase inhibitor family. Its transcription is regulated in combinatorial fashion by Ets, p53 and AP-1. It is present in normal breast and prostatic epithelial cells but downregulated in the respective carcinomas. The extent of downregulation correlates with the progression of the carcinoma and may help in prognosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: clade B (ovalbumin); member 5; peptidase inhibitor 5; PI-5; protease inhibitor 5 (maspin); serine (or cysteine) proteinase inhibitor; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 5; serpin B5
Gene Aliases: maspin; PI5
UniProt ID: (Human) P36952
Entrez Gene ID: (Human) 5268
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