|Immunohistochemistry (Paraffin) (IHC (P))||1:2000|
|Western Blot (WB)||Assay Dependent|
|Western Blot (WB)||See 2 publications below|
|Immunocytochemistry (ICC)||See 1 publications below|
|Immunohistochemistry (IHC)||See 8 publications below|
|Tested Species reactivity||Human|
|Published species reactivity||Dog , Rat Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Purified human skin chymase|
|Storage buffer||PBS, pH 7.4, with 0.2% BSA|
|Contains||0.09% sodium azide|
|Storage conditions||4° C|
MA5-11717 targets Mast Cell Chymase in IHC (P) and WB applications and shows reactivity with Human samples.
The MA5-11717 immunogen is purified human skin chymase.
Mast cells contain a number of preformed chemical mediators such as histamine, chymase, carboxypeptidase and proteolytic tryptase. A substantial quantity of chymase is estimated to be found in mast cells of skin and lung and suggestes this enzyme plays a major role in mast cell mediated events. Human mast cell chymase is considered to be an important marker of mast cells as well as an important mediator of inflammation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Alpha-chymase; Chymase; chymase 1 preproprotein transcript E; chymase 1 preproprotein transcript I; chymase 1, mast cell; chymase, heart; chymase, mast cell; heart; mast cell; Mast cell protease I
Gene Aliases: chymase; CMA1; CYH; CYM; MCT1
UniProt ID: (Human) P23946
Entrez Gene ID: (Human) 1215
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