|Immunocytochemistry (ICC)||2 µg/ml|
|Immunofluorescence (IF)||2 ug/ml|
|Western Blot (WB)||2 µg/ml|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A 13 amino acid peptide near the center of human MettL7A.|
|Purification||Antigen affinity chromatography|
|Contains||0.02% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
A suggested positive control is MCF7 cell lysate.
PA5-20636 can be used with blocking peptide PEP-0756.
MettL7A belongs to the methyltransferase superfamily. It is a probable methyltransferase. Methyltransferase is a type of transferase enzyme which transfers a methyl group from a donor to an acceptor. Often methylation occurs on nucleic bases in DNA or amino acids in protein structures. DNA methylation is often utilized to silence and regulate genes without changing the original DNA sequence. DNA methylation may be necessary for normal growth from embryonic stages in mammals. When mutant embryonic stem cells lacking the murine DNA methyltransferase gene were introduced to a germline of mice they caused a recessive lethal phenotype. Methylation may also be linked to cancer development as methylation of tumor suppressor genes promotes tumorgenesis and metastasis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: methyltransferase like 7A; Methyltransferase-like protein 7A; PRO0066, AAM-B; Protein AAM-B
Gene Aliases: 2210414H16Rik; 3300001H21Rik; AAM-B; METTL7A; PRO0066; UbiE1; UNQ1902/PRO4348
UniProt ID: (Human) Q9H8H3
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.